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pentobarbital will lower the level or effect of elbasvir/grazoprevir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic result of elbasvir/grazoprevir could be reduced if coadministered with robust CYP3A inducers and is also therefore contraindicated.pentobarbital will lower the extent or impact of doxorubici